Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935465 | 0.95 | SLC9A1 (0.72) | SLC9A1 | |
| SCHEMBL9018727 | 0.90 | SLC9A1 (0.68) | SLC9A1 | |
| SCHEMBL8531034 | 0.89 | SLC9A1 (0.76) | SLC9A1 | |
| SCHEMBL8612833 | 0.86 | SLC9A1 (0.64) | SLC9A1 | |
| Rimeporide SCHEMBL1019633 | 0.84 | SLC9A1 (1.00) | SLC9A1 | |
| Rimeporide SCHEMBL30309010 | 0.84 | SLC9A1 (1.00) | SLC9A1 | |
| SCHEMBL6930558 | 0.83 | SLC9A1 (0.59) | SLC9A1 | |
| SCHEMBL8531009 | 0.83 | SLC9A1 (0.85) | SLC9A1 | |
| Rimeporide SCHEMBL16712399 | 0.83 | SLC9A1 (0.97) | SLC9A1 | |
| Rimeporide SCHEMBL1022632 | 0.83 | SLC9A1 (0.97) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131064-A2 | USE OF BENZOYLGUANIDINES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS | MERCK PATENT GmbH (DE) | 2001-09-12 | — | — | EP | claimed |
| EP-0743301-B1 | Benzoylguanidines containing fluorine | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | EP | claimed |
| WO-2000030624-A2 | USE OF BENZOYLGUANIDINES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS | MERCK PATENT GMBH (DE) | 2000-06-02 | — | — | WO | claimed |
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | claimed |
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | claimed |
| JP-8311011-A | — | — | None | — | — | JP | disclosed |
| EP-1131064-A2 | USE OF BENZOYLGUANIDINES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS | MERCK PATENT GmbH (DE) | 2001-09-12 | — | — | EP | disclosed |
| EP-0743301-B1 | Benzoylguanidines containing fluorine | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000030624-A2 | USE OF BENZOYLGUANIDINES FOR THE TREATMENT OF NON-INSULIN-DEPENDENT DIABETES MELLITUS | MERCK PATENT GMBH (DE) | 2000-06-02 | — | — | WO | disclosed |
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |
| JP-H08311011-A | FLUORINE-CONTAINING BENZOYGUANIDINE | MERCK PATENT GMBH | 1996-11-26 | — | — | JP | disclosed |
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |