Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 9/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901979 | 0.81 | HTR2A (0.46) | HTR2AHTR2CHTR2B | |
| SCHEMBL2360390 | 0.79 | KDM1A (0.52) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL11965121 | 0.79 | HTR2A (0.44) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL2324658 | 0.79 | KDM1A (0.52) | KDM1AMAOBKCNH2RCOR1MEN1 | |
| SCHEMBL6250772 | 0.79 | KDM1A (0.47) | KDM1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL2359931 | 0.79 | HTR2A (0.44) | HTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL2854689 | 0.79 | KDM1A (0.52) | KDM1AMAOBKCNH2RCOR1MEN1 | |
| SCHEMBL2827719 | 0.79 | KDM1A (0.52) | KDM1AMAOBKCNH2RCOR1MEN1 | |
| SCHEMBL446481 | 0.78 | MAOB (0.48) | KDM1AMAOBKCNH2RCOR1MAPT | |
| SCHEMBL446482 | 0.78 | MAOB (0.48) | KDM1AMAOBKCNH2RCOR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849262-B1 | Aminophenyl ketone derivatives and a method for the preparation thereof | AMERICAN CYANAMID CO (US) | 2001-10-17 | — | — | EP | claimed |