Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612265 | 0.95 | SLC9A1 (0.61) | SLC9A1 | |
| SCHEMBL8442619 | 0.90 | SLC9A1 (0.70) | SLC9A1 | |
| SCHEMBL8438219 | 0.84 | SLC9A1 (0.74) | SLC9A1 | |
| SCHEMBL9018724 | 0.82 | SLC9A1 (0.67) | SLC9A1 | |
| SCHEMBL9018688 | 0.82 | SLC9A1 (0.67) | SLC9A1 | |
| SCHEMBL8438810 | 0.82 | SLC9A1 (0.70) | SLC9A1 | |
| SCHEMBL7797862 | 0.81 | EGLN1 (0.43) | SLC9A1 | |
| SCHEMBL9018675 | 0.81 | SLC9A1 (0.57) | SLC9A1 | |
| SCHEMBL8439131 | 0.81 | SLC9A1 (0.68) | SLC9A1 | |
| Rimeporide SCHEMBL1019633 | 0.81 | SLC9A1 (1.00) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-B1 | Benzoylguanidines containing fluorine | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | EP | claimed |
| EP-0743301-B1 | Benzoylguanidines containing fluorine | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | EP | disclosed |
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |