Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 2/20 | 0.55 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916785 | 0.89 | DPP8 (0.54) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL147036 | 0.88 | DPP8 (0.59) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL11198623 | 0.87 | DPP8 (0.58) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL10500161 | 0.86 | DPP8 (0.58) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL15456527 | 0.86 | HTT (0.61) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL10756101 | 0.86 | DPP8 (0.59) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL6418689 | 0.85 | DPP8 (0.58) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL11160001 | 0.85 | HTT (0.63) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL13647947 | 0.84 | MGLL (0.67) | DPP8DPP9TGM2MGLLRAB9A | |
| SCHEMBL10825541 | 0.84 | DPP8 (0.57) | DPP8DPP9TGM2MGLLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777674-B1 | POLYNUCLEOTIDE REAGENTS HAVING NONNUCLEOTIDIC MOIETIES, AND ASSOCIATED METHODS OF SYNTHESIS AND USE | BAYER AG (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0777674-A1 | POLYNUCLEOTIDE REAGENTS HAVING NONNUCLEOTIDIC MOIETIES, AND ASSOCIATED METHODS OF SYNTHESIS AND USE | CHIRON CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5597909-A | Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use | CHIRON CORPORATION (US) | 1997-01-28 | — | — | US | disclosed |
| US-5594117-A | Polynucleotide reagents containing modified deoxyribose moieties and associated methods of synthesis and use | CHIRON CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1996006104-A1 | POLYNUCLEOTIDE REAGENTS HAVING NONNUCLEOTIDIC MOIETIES, AND ASSOCIATED METHODS OF SYNTHESIS AND USE | CHIRON CORPORATION (US) | 1996-02-29 | — | — | WO | disclosed |