Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29771752 | 1.00 | LMNA (0.66) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL29246738 | 0.86 | LMNA (0.49) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL29771743 | 0.86 | LMNA (0.49) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL14048033 | 0.84 | PTPN1 (0.51) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL29771722 | 0.84 | PTPN1 (0.51) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL23783245 | 0.84 | LMNA (0.70) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL30427017 | 0.84 | LMNA (0.60) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL22836575 | 0.84 | LMNA (0.60) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL3431542 | 0.84 | LMNA (0.69) | LMNAPOLBALDH1A1KDM4EPRKDC | |
| SCHEMBL10969853 | 0.84 | LMNA (0.68) | LMNAPOLBALDH1A1KDM4EPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853652-B | Sulfonium salt compound, preparation method and application thereof, and cationic UV (ultraviolet) curing adhesive | 韦尔通科技股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-114853652-A | Sulfonium salt compound, preparation method and application thereof, and cationic UV (ultraviolet) curing adhesive | 韦尔通(厦门)科技股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| US-20010025045-A1 | Substituted isoquinoline derivatives and their use as anticonvulsants | SMITHKLINE BEECHAM P.L.C. | 2001-09-27 | — | — | US | disclosed |
| EP-1025087-A1 | SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021836-A1 | SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025045-A1 | Substituted isoquinoline derivatives and their use as anticonvulsants | INA, GRIN2C, GRIN2A | LMNA 3590/4885POLB 3366/4885ALDH1A1 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.