Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27888004 | 0.92 | EPHX2 (0.50) | EPHX2ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8072282 | 0.85 | EPHX2 (0.56) | EPHX2EPHX1ALDH1A1KMT2AMEN1 | |
| SCHEMBL4655543 | 0.83 | EPHX2 (0.64) | EPHX2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL28056996 | 0.82 | EPHX2 (0.42) | EPHX2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2706390 | 0.82 | EPHX2 (0.63) | EPHX2EPHX1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28032139 | 0.79 | OPRM1 (0.40) | EPHX2ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3397254 | 0.77 | EPHX2 (1.00) | EPHX2EPHX1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5051924 | 0.77 | EPHX2 (1.00) | EPHX2EPHX1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6437914 | 0.76 | EPHX2 (0.48) | EPHX2EPHX1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1301606 | 0.76 | CYP19A1 (0.71) | EPHX2ALDH1A1KMT2AHPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104940202-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-104968345-B | 1, 5-naphthyridine derivatives and ME L K inhibitors containing 1, 5-naphthyridine derivatives | 肿瘤疗法科学股份有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-106565510-B | The preparation method of trans 4- Amino-cyclohexvls acetic ester derivative | 浙江京新药业股份有限公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-106905386-A | Aminoglycoside derivative | 莱姆派克斯制药公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-106565510-A | Preparation method for trans 4-amino-cyclohexyl acetate derivative | 浙江京新药业股份有限公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-1751025-B | Diamine derivatives | DAIICHI SEIYAKU CO | 2010-05-12 | — | — | CN | disclosed |
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |