Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Anhydride SCHEMBL27671012 | 0.90 | TDP1 (0.78) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL23672547 | 0.88 | ALOX15 (0.67) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL18038400 | 0.87 | TDP1 (0.93) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL27554004 | 0.87 | TDP1 (0.93) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL9718937 | 0.85 | TDP1 (0.70) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL5482953 | 0.85 | TDP1 (0.70) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL7798198 | 0.84 | TDP1 (0.61) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL220 | 0.84 | TDP1 (1.00) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL380499 | 0.84 | TDP1 (1.00) | TDP1ALOX15TRPA1ALDH1A1TSHR | |
| Phthalic Anhydride SCHEMBL29356227 | 0.84 | TDP1 (1.00) | TDP1ALOX15TRPA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |