Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155982 | 0.91 | HSD17B10 (0.61) | HSD17B10CXCL8TAAR1MAPTMEN1 | |
| SCHEMBL29431297 | 0.91 | HSD17B10 (0.61) | HSD17B10CXCL8TAAR1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL2527513 | 0.90 | HSD17B10 (0.59) | HSD17B10CXCL8TAAR1MAPTMEN1 | |
| SCHEMBL28215186 | 0.90 | HSD17B10 (0.59) | HSD17B10CXCL8TAAR1MAPTMEN1 | |
| SCHEMBL2528595 | 0.86 | AKR1B1 (0.61) | CXCL8MAPTTDP1MEN1KMT2A | |
| SCHEMBL29631318 | 0.86 | AKR1B1 (0.61) | CXCL8MAPTTDP1MEN1KMT2A | |
| SCHEMBL8285 | 0.86 | AKR1B1 (0.61) | CXCL8MAPTTDP1MEN1KMT2A | |
| SCHEMBL7798248 | 0.85 | TDP1 (0.53) | TAAR1MAPTTDP1MEN1KMT2A | |
| Anisole SCHEMBL30186745 | 0.85 | HSD17B10 (0.63) | HSD17B10CXCL8TAAR1MAPTTDP1 | |
| Ammonia Solution, Strong SCHEMBL22042026 | 0.84 | CTBP2 (0.59) | CXCL8MAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |