Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059781 | 0.92 | L3MBTL1 (0.55) | TDP1MAPTL3MBTL1MEN1TSHR | |
| SCHEMBL28267690 | 0.88 | CTBP2 (0.53) | MAPTMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL7798245 | 0.85 | HSD17B10 (0.53) | TDP1MAPTL3MBTL1MAPK1MEN1 | |
| SCHEMBL4059783 | 0.83 | MTNR1A (0.51) | TDP1MAPTL3MBTL1MEN1TSHR | |
| SCHEMBL468013 | 0.81 | MEN1 (0.58) | TDP1MAPTL3MBTL1MEN1TSHR | |
| SCHEMBL30027909 | 0.81 | MEN1 (0.58) | TDP1MAPTL3MBTL1MEN1TSHR | |
| SCHEMBL1792326 | 0.80 | TSHR (0.55) | TDP1MAPTL3MBTL1MEN1TSHR | |
| SCHEMBL27833130 | 0.80 | CTBP2 (0.49) | MAPTMEN1KMT2ASMN1; SMN2TAAR1 | |
| SCHEMBL30522283 | 0.79 | CTBP2 (0.51) | MAPTL3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL265432 | 0.79 | CTBP2 (0.51) | MAPTL3MBTL1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |