Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8686842 | 1.00 | MAPT (0.41) | MAPTTP53KDM4EALDH1A1POLB | |
| SCHEMBL7798614 | 0.82 | KMT2A (0.38) | MAPTTP53KDM4EALDH1A1POLB | |
| SCHEMBL8683741 | 0.82 | KMT2A (0.38) | MAPTTP53KDM4EALDH1A1POLB | |
| SCHEMBL7800541 | 0.80 | TP53 (0.44) | MAPTTP53KDM4EALDH1A1POLB | |
| SCHEMBL8681553 | 0.80 | TP53 (0.44) | MAPTTP53KDM4EALDH1A1POLB | |
| SCHEMBL7792873 | 0.80 | BRPF1 (0.53) | MAPTTP53KDM4EALDH1A1POLB | |
| SCHEMBL8682973 | 0.80 | BRPF1 (0.53) | MAPTTP53KDM4EALDH1A1POLB | |
| SCHEMBL7798656 | 0.78 | MAPT (0.46) | MAPTTP53KDM4EALDH1A1MEN1 | |
| SCHEMBL8683076 | 0.78 | MAPT (0.46) | MAPTTP53KDM4EALDH1A1MEN1 | |
| SCHEMBL8681564 | 0.77 | MAPT (0.47) | MAPTTP53KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708093-B1 | Quinoxalines, process for their preparation, and their use | AVENTIS PHARMA GMBH (DE) | 2001-01-17 | — | — | EP | disclosed |