SCHEMBL7798574

SCHEMBL7798574

CCc1cc(SC)c(S(C)(=O)=O)cc1C(=O)N=C(N)N

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792897 0.88 SLC9A1 (0.53) SLC9A1
SCHEMBL7801572 0.87 SLC9A1 (0.52) SLC9A1
SCHEMBL7800488 0.86 SLC9A1 (0.51) SLC9A1
SCHEMBL6932523 0.86 SLC9A1 (0.68) SLC9A1
SCHEMBL8534951 0.85 SLC9A1 (0.61) SLC9A1
SCHEMBL7798356 0.84 SLC9A1 (0.74) SLC9A1
SCHEMBL7801930 0.83
SCHEMBL7798529 0.83
SCHEMBL8533047 0.82 SLC9A1 (0.67) SLC9A1
SCHEMBL8441408 0.82 SLC9A1 (0.58) SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725062-B1 4-mercapto-benzoylguanidine derivatives MERCK PATENT GMBH (DE) 2001-06-13 EP disclosed
US-5696167-A 4-mercaptobenzoylguanidine derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1997-12-09 US disclosed
EP-0725062-A1 4-mercapto-benzoylguanidine derivatives MERCK PATENT GmbH (DE) 1996-08-07 EP disclosed