SCHEMBL7798728

SCHEMBL7798728

Cc1ccc(C=Cc2ccc(C=O)o2)o1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.55
ALDH1A1 P00352 8/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
HTT P42858 4/20 0.49
KDM4E B2RXH2 3/20 0.49
PKM P14618 2/20 0.49
GAA P10253 1/20 0.45
ALOX5 P09917 2/20 0.44
SMN1; SMN2 Q16637 4/20 0.42
RAB9A P51151 3/20 0.42
LMNA P02545 2/20 0.42
NPC1 O15118 2/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19759508 1.00 MAPT (0.55) MAPTALDH1A1MEN1KMT2AHTT
5-Methylfurfural SCHEMBL51606 0.91
5-Methylfurfural SCHEMBL4463513 0.89
SCHEMBL12307012 0.86 MAPT (0.61) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL14461124 0.86 MAPT (0.61) MAPTALDH1A1MEN1KMT2AHTT
5-Methylfurfural SCHEMBL23611458 0.81 ALDH1A1 (0.53) MAPTALDH1A1MEN1KMT2AHTT
5-Methylfurfural SCHEMBL28511742 0.81 GAA (0.48) MAPTALDH1A1MEN1KMT2AHTT
5-Methylfurfural SCHEMBL28207842 0.81 ALDH1A1 (0.58) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL8807218 0.78 MAPT (0.55) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL14608728 0.78 MAPT (0.55) MAPTALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1162209-A1 Acetal copolymers and use thereof in photosensitive compositions Kodak Polychrome Graphics Company Ltd. (US) 2001-12-12 EP disclosed
US-6270938-B1 FOR LITHOGRAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC 2001-08-07 US disclosed