Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648611 | 0.94 | TDP1 (0.55) | MAPTTDP1ALDH1A1LMNACYP1A2 | |
| SCHEMBL29233387 | 0.88 | TDP1 (0.56) | MAPTTDP1ALDH1A1LMNACYP1A2 | |
| SCHEMBL351318 | 0.87 | MAPT (0.64) | MAPTTDP1ALDH1A1TSHRSLC1A5 | |
| SCHEMBL1648609 | 0.87 | TDP1 (0.57) | MAPTTDP1ALDH1A1LMNACYP1A2 | |
| SCHEMBL29162948 | 0.85 | MAPT (0.62) | MAPTTDP1ALDH1A1TSHRSLC1A5 | |
| SCHEMBL2788019 | 0.84 | MAPT (0.51) | MAPTTDP1ALDH1A1LMNACYP1A2 | |
| SCHEMBL23532588 | 0.82 | TDP1 (0.72) | TDP1ALDH1A1LMNACYP1A2TSHR | |
| Benzoic Acid SCHEMBL10978494 | 0.82 | ALDH1A1 (0.68) | MAPTTDP1ALDH1A1LMNATSHR | |
| SCHEMBL10948819 | 0.81 | MAPT (0.54) | MAPTTDP1ALDH1A1LMNACYP1A2 | |
| Phosphonic Acid SCHEMBL11767971 | 0.81 | MAPT (0.57) | MAPTALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747323-B1 | Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same | AMCOL INTERNATIONAL CORP (US) | 2001-12-12 | — | — | EP | claimed |
| EP-0747323-A1 | Intercalates; exfoliates; process for manufacturing intercalates and exfoliates and composite materials containing same | AMCOL INTERNATIONAL CORPORATION (US) | 1996-12-11 | — | — | EP | claimed |