⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7056109 | 0.80 | — | — | |
| SCHEMBL2026374 | 0.76 | — | — | |
| SCHEMBL136992 | 0.75 | — | — | |
| SCHEMBL14557372 | 0.72 | — | — | |
| SCHEMBL4075401 | 0.71 | — | — | |
| SCHEMBL14823917 | 0.71 | — | — | |
| SCHEMBL7120179 | 0.67 | — | — | |
| SCHEMBL5699013 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL4075445 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL18221756 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980870-B1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | WACKER CHEMIE GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6156918-A | Process for the preparation of silanes, with a tertiary hydrocarbon group in the a-position relative to the silicon atom | WACKER-CHEMIE GMBH (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-1050536-A2 | 2-(Benz-)Imidazol-, 2-(Benz-)Oxazol- or 2-(Benz-)Thiazol-substituted Silanes | Wacker-Chemie GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |
| EP-0980870-A1 | Process for preparing silanes substituted at position alpha of the silicon atom by a tertiary hydrocarbon group | Wacker-Chemie GmbH (DE) | 2000-02-23 | — | — | EP | disclosed |
| EP-0963992-A2 | Method for preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING CORPORATION (US) | 1999-12-15 | — | — | EP | disclosed |
| US-5872274-A | Method for preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING CORPORATION (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0405560-B2 | Preparation of tertiary-hydrocarbylsilyl compounds | DOW CORNING TORAY SILICONE (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5068386-A | PREPARATION OF TERTIARY-HYDROCARBYLSILYL COMPOUNDS | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0405560-A2 | Preparation of tertiary-hydrocarbylsilyl compounds | Dow Corning Toray Silicone Company, Limited (JP) | 1991-01-02 | — | — | EP | disclosed |
| US-4801719-A | PROTECTIVE GROUP REAGENT FOR ORGANIC SYNTHESIS | CIBA-GEIGY CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |
| US-4695643-A | Silanes, process for their preparation, and their use | CIBA-GEIGY CORPORATION (US) | 1987-09-22 | — | — | US | disclosed |