SCHEMBL7799301

SCHEMBL7799301

C=C(C)C(=O)OCCC[SiH2]OC(C)OCC

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.45
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20555058 0.87 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8722391 0.85 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL432361 0.83 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2491517 0.82 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL22115857 0.82 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7641426 0.81 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7876345 0.81 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2568271 0.79 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1225134 0.79 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL137795 0.79 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6329456-B1 FOR FORMING A COATING FILM OF HIGH HARDNESS, HEAT RESISTANCE AND WEATHERABILITY MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2001-12-11 US disclosed
US-6090873-A ACRYLATE TERPOLYMER CONTAINING EPOXY AND ALKOXYSILANE GROUPS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2000-07-18 US disclosed
EP-0822240-A1 COATING RESIN COMPOSITION MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1998-02-04 EP disclosed