SCHEMBL8722391

SCHEMBL8722391

C=C(C)C(=O)OCCC[SiH2]OC(C)OC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.40
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL432361 0.86 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL7799301 0.85 TSHR (0.47) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL2491517 0.84 TSHR (0.49) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL5606172 0.82 TSHR (0.41) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1225134 0.81 TSHR (0.49) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL7637133 0.81 TSHR (0.40) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28374752 0.81 TSHR (0.45) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL345837 0.80 TSHR (0.55) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL7876345 0.80 TSHR (0.51) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL28293056 0.79 TSHR (0.53) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116802234-A Method for producing crosslinkable materials based on organoalkoxysilane-terminated polymers 瓦克化学股份公司 2023-09-22 CN disclosed
US-5834396-A THE DYE-CONTAINING LAYER/SUBSTRATE HAVING A HEAT- AND FRICTION-RESISTANT TOP LAYER; ANTISOILANTS AND -STICKING AGENTS; RESOLUTION; PRINTERS AND COPIERS USING AN N-TIMES SPEED MODE; STORAGE STABILITY RICOH COMPANY, LTD. (JP) 1998-11-10 US disclosed