SCHEMBL7799561

SCHEMBL7799561

CCC1=Cc2cc(C(=O)O)ccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.46
ALDH1A1 P00352 4/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
TTR P02766 1/20 0.41
PTPRC P08575 2/20 0.40
KDM4E B2RXH2 3/20 0.39
GAA P10253 3/20 0.39
MAPT P10636 2/20 0.39
TSHR P16473 2/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39
GFER P55789 1/20 0.39
PLEC Q15149 1/20 0.39
BCL2 P10415 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717095 0.75 ALDH1A1 (0.54) POLBALDH1A1KMT2AMEN1NPC1
SCHEMBL2755400 0.72 ALDH1A1 (0.56) POLBALDH1A1KMT2AMEN1NPC1
Hydrochloric Acid SCHEMBL10354232 0.71 ALDH1A1 (0.54) POLBALDH1A1KMT2AMEN1NPC1
SCHEMBL2591830 0.69 EPHX2 (0.54) ALDH1A1KMT2AMEN1NPC1RAB9A
SCHEMBL1355542 0.69 ALDH1A1 (0.52) POLBALDH1A1KMT2AMEN1NPC1
SCHEMBL2585314 0.69 KDM4E (0.59) POLBALDH1A1KMT2AMEN1NPC1
SCHEMBL30269683 0.69 GAA (0.61) POLBALDH1A1KMT2AMEN1NPC1
SCHEMBL3131960 0.69 GAA (0.61) POLBALDH1A1KMT2AMEN1NPC1
SCHEMBL9652658 0.69 SRD5A2 (0.57) POLBALDH1A1NPC1RAB9ARXRA
SCHEMBL23699534 0.68 ALDH1A1 (0.50) POLBALDH1A1KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599886-B1 MACROMONOMERS HAVING REACTIVE END GROUPS MISSISSIPPI POLYMER TECH INC (US) 2001-03-21 EP disclosed
US-5973075-A POLYPHENYL RESINS MAXDEM INCORPORATION (US) 1999-10-26 US disclosed
US-5827927-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1998-10-27 US disclosed
US-5824744-A RIGID POLYMER RODS AND MACROMONOMERS WITH REACTIVE END GROUPS FOR REINFORCEMENT MAXDEM INCORPORATED (US) 1998-10-20 US disclosed
US-5670564-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1997-09-23 US disclosed
EP-0599886-A4 MACROMONOMERS HAVING REACTIVE END GROUPS. MAXDEM INC (US) 1996-07-24 EP disclosed
EP-0599886-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1994-06-08 EP disclosed
WO-1993004099-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1993-03-04 WO disclosed