SCHEMBL7799593

SCHEMBL7799593

Cc1ccc(C=Cc2ccc(C=O)s2)s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
MAPT P10636 10/20 0.48
RAB9A P51151 6/20 0.48
NPC1 O15118 5/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
CASP3 P42574 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
KMT2A Q03164 8/20 0.45
MEN1 O00255 6/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 5/20 0.42
HPGD P15428 4/20 0.42
RECQL P46063 2/20 0.42
THRB P10828 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40949 0.91
SCHEMBL14433026 0.89 PTGS1 (0.59) PTGS1PTGS2MAPTRAB9ANPC1
SCHEMBL12307008 0.86 MAPT (0.61) PTGS1PTGS2MAPTRAB9ANPC1
SCHEMBL13226178 0.86 MAPT (0.61) PTGS1PTGS2MAPTRAB9ANPC1
SCHEMBL16533088 0.86 ALDH1A1 (0.43) MAPTALDH1A1HPGDCYP3A4CYP2C9
SCHEMBL8946118 0.84 MAPT (0.50) PTGS1PTGS2MAPTRAB9ANPC1
Acetic Acid SCHEMBL28207221 0.81 MAPT (0.47) PTGS1PTGS2MAPTRAB9ANPC1
SCHEMBL23665410 0.80 PTGS1 (0.52) PTGS1PTGS2MAPTRAB9ANPC1
SCHEMBL10744371 0.78 MAPT (0.48) PTGS1PTGS2MAPTRAB9ANPC1
SCHEMBL10674835 0.78 DPP4 (0.53) MAPTRAB9ANPC1SMN1; SMN2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1162209-A1 Acetal copolymers and use thereof in photosensitive compositions Kodak Polychrome Graphics Company Ltd. (US) 2001-12-12 EP disclosed
US-6270938-B1 FOR LITHOGRAPHIC PRINTING PLATES KODAK POLYCHROME GRAPHICS LLC 2001-08-07 US disclosed