SCHEMBL7799652

SCHEMBL7799652

CC(=O)Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.69
HPGD P15428 2/20 0.69
LMNA P02545 3/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PPARG P37231 2/20 0.57
PPARA Q07869 2/20 0.57
FABP2 P12104 1/20 0.57
SLC22A12 Q96S37 1/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
MAPT P10636 3/20 0.56
HSD17B10 Q99714 1/20 0.56
MAPK1 P28482 2/20 0.55
SRD5A2 P31213 1/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
CYP11B1 P15538 1/20 0.51
CYP11B2 P19099 1/20 0.51
USP2 O75604 1/20 0.50
ABCB11 O95342 1/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76135 0.92 LMNA (0.64) ELANEHPGDLMNAL3MBTL1PPARA
Hydrochloric Acid SCHEMBL27466889 0.90 LMNA (0.61) ELANEHPGDLMNAL3MBTL1PPARA
Ammonia Solution, Strong SCHEMBL22437493 0.90 LMNA (0.61) ELANEHPGDLMNAL3MBTL1PPARA
SCHEMBL27364336 0.90 LMNA (0.61) ELANEHPGDLMNAL3MBTL1PPARA
SCHEMBL18184942 0.90 LMNA (0.61) ELANEHPGDLMNAL3MBTL1PPARA
SCHEMBL9339013 0.89 ELANE (0.83) ELANELMNAMAPTHSD17B10MEN1
Nitrogen SCHEMBL27903819 0.88 LMNA (0.59) ELANEHPGDLMNAL3MBTL1PPARA
SCHEMBL10339728 0.86 ELANE (0.66) ELANEHPGDLMNAL3MBTL1PPARG
SCHEMBL29172384 0.86 HSD17B10 (0.63) ELANEHPGDLMNAPPARASMN1; SMN2
SCHEMBL8458974 0.86 ELANE (0.66) ELANEHPGDLMNAL3MBTL1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2252730-A None JP disclosed
CN-112189004-B Process for preparing keto-functionalized aromatic (meth) acrylated products 赢创运营有限公司 2023-12-15 CN disclosed
CN-112189004-A Method for producing keto-functionalized aromatic (meth) acrylates 赢创运营有限公司 2021-01-05 CN disclosed
EP-3652139-B1 METHOD FOR PREPARING KETO-FUNCTIONALIZED AROMATIC (METH)ACRYLATES EVONIK OPERATIONS GMBH (DE) 2020-09-23 EP disclosed
EP-0599886-B1 MACROMONOMERS HAVING REACTIVE END GROUPS MISSISSIPPI POLYMER TECH INC (US) 2001-03-21 EP disclosed
US-5973075-A POLYPHENYL RESINS MAXDEM INCORPORATION (US) 1999-10-26 US disclosed
US-5827927-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1998-10-27 US disclosed
US-5824744-A RIGID POLYMER RODS AND MACROMONOMERS WITH REACTIVE END GROUPS FOR REINFORCEMENT MAXDEM INCORPORATED (US) 1998-10-20 US disclosed
US-5670564-A Macromonomers having reactive end groups MAXDEM INCORPORATED (US) 1997-09-23 US disclosed
EP-0599886-A4 MACROMONOMERS HAVING REACTIVE END GROUPS. MAXDEM INC (US) 1996-07-24 EP disclosed
EP-0599886-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1994-06-08 EP disclosed
WO-1993004099-A1 MACROMONOMERS HAVING REACTIVE END GROUPS MAXDEM INCORPORATED (US) 1993-03-04 WO disclosed
JP-H02252730-A PRODUCTION OF POLYARYL ETHER KETONE TEIJIN LTD 1990-10-11 JP disclosed