SCHEMBL7799663

SCHEMBL7799663

CCCCCCCCCCc1cccc(CCCCCCCCCC)c1CCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.57
KCNH2 Q12809 2/20 0.52
BID P55957 3/20 0.51
MCL1 Q07820 3/20 0.51
BCL2L1 Q07817 2/20 0.51
BAK1 Q16611 2/20 0.51
KAT8 Q9H7Z6 2/20 0.51
PPARA Q07869 2/20 0.51
PPARG P37231 1/20 0.51
EP300 Q09472 1/20 0.51
KAT2A Q92830 1/20 0.51
KAT2B Q92831 1/20 0.51
KAT5 Q92993 1/20 0.51
SAE1 Q9UBE0 1/20 0.51
ALOX5 P09917 2/20 0.50
PTGS2 P35354 1/20 0.50
TYR P14679 2/20 0.48
CYSLTR2 Q9NS75 1/20 0.47
CYSLTR1 Q9Y271 1/20 0.47
NR1H2 P55055 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30301799 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL30581335 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL9123772 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL11341318 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL5675055 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL7265082 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL5421151 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL4078754 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL8405915 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1
SCHEMBL11326716 1.00 LIPG (0.57) LIPGKCNH2BIDMCL1BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586258-B1 Sulfurized overbased compositions LUBRIZOL CORP (US) 2001-11-28 EP disclosed
US-5484542-A OIL ADDITIVES THE LUBRIZOL CORPORATION (US) 1996-01-16 US disclosed
EP-0586258-A2 Sulfurized overbased compositions The Lubrizol Corporation (US) 1994-03-09 EP disclosed
EP-0301029-B1 USE OF GREASE AND GEAR LUBRICANT COMPOSITIONS COMPRISING AT LEAST ONE METAL-CONTAINING COMPOSITION AND AT LEAST ONE SULFURIZED ORGANIC COMPOUND LUBRIZOL CORP (US) 1994-01-05 EP disclosed
US-5055626-A Novel lubricants MOBIL OIL CORPORATION (US) 1991-10-08 US disclosed
EP-0301029-A1 USE OF GREASE AND GEAR LUBRICANT COMPOSITIONS COMPRISING AT LEAST ONE METAL-CONTAINING COMPOSITION AND AT LEAST ONE SULFURIZED ORGANIC COMPOUND. LUBRIZOL CORP (US) 1989-02-01 EP disclosed
WO-1987006256-A2 GREASE AND GEAR LUBRICANT COMPOSITIONS COMPRISING AT LEAST ONE METAL-CONTAINING COMPOSITION AND AT LEAST ONE SULFURIZED ORGANIC COMPOUND THE LUBRIZOL CORPORATION (US) 1987-10-22 WO disclosed
EP-0094261-B1 ONE-COMPONENT MOISTURE CURABLE URETHANE COATING SYSTEM The Lubrizol Corporation (US) 1986-12-03 EP disclosed
EP-0094196-B1 TWO-COMPONENT URETHANE COATING SYSTEM The Lubrizol Corporation (US) 1986-08-27 EP disclosed
US-4468339-A AND SOLUBILIZER WHICH IS REACTION OF CARBOXYLIC ACID ACYLATING AGENT WITH HYDROCARBON SUBSTITMENT AND HYDROXYAMINE THE LUBRIZOL CORPORATION (US) 1984-08-28 US disclosed
US-4443577-A COLLOIDAL DISPERSE SYSTEM, OVERBASED SALTS THE LUBRIZOL CORPORATION (US) 1984-04-17 US disclosed
US-4436855-A DIISOCYANATE AND ORGANIC PHOSPHATE THE LUBRIZOL CORPORATION (US) 1984-03-13 US disclosed
EP-0094261-A2 One-component moisture curable urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
EP-0094196-A2 Two-component urethane coating system The Lubrizol Corporation (US) 1983-11-16 EP disclosed
EP-0084966-A2 Aqueous compositions containing overbased materials The Lubrizol Corporation (US) 1983-08-03 EP disclosed