Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517469 | 0.88 | GCGR (0.45) | GCGR | |
| SCHEMBL10518455 | 0.86 | GCGR (0.44) | GCGR | |
| SCHEMBL8021235 | 0.79 | GCGR (0.42) | GCGR | |
| SCHEMBL8949777 | 0.79 | GCGR (0.74) | GCGR | |
| SCHEMBL9384902 | 0.78 | GCGR (0.47) | GCGR | |
| SCHEMBL8949822 | 0.78 | GCGR (0.88) | GCGR | |
| SCHEMBL7791791 | 0.76 | GCGR (0.40) | GCGR | |
| SCHEMBL2656279 | 0.76 | GCGR (1.00) | GCGR | |
| SCHEMBL9383080 | 0.76 | GCGR (0.53) | GCGR | |
| SCHEMBL10424217 | 0.75 | GCGR (0.62) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535548-B1 | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL IND LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| US-6162798-A | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2000-12-19 | — | — | US | disclosed |
| EP-0339358-B1 | Pyrazolopyridine type mevalonolactones | NISSAN CHEMICAL IND LTD (JP) | 1994-07-13 | — | — | EP | disclosed |
| EP-0535548-A1 | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5024999-A | Anti-hyperlipidemia, anti-atherosclerosis agents | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| WO-1989010365-A1 | PYRAZOLOPYRIDINE TYPE MEVALONOLACTONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-02 | — | — | WO | disclosed |
| EP-0327500-A2 | 5-Substituted 1H-pyrazolo[3,4-b]pyridine derivatives, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1989-08-09 | — | — | EP | disclosed |
| US-4822799-A | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals | SANDOZ PHARM. CORP. (US) | 1989-04-18 | — | — | US | disclosed |