Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799826 | 0.77 | CYP3A4 (0.45) | ADORA2BHTTMAPK1MAPTCYP3A4 | |
| SCHEMBL7799619 | 0.76 | ADORA2B (0.32) | ADORA2BSMN1; SMN2MAPTCYP3A4ADRA2A | |
| SCHEMBL7799618 | 0.68 | ADORA2B (0.32) | ADORA2BMAPTCYP3A4ADRA2AADRA2B | |
| SCHEMBL10838399 | 0.64 | KDM4E (0.35) | ADORA2BLMNAMAPK1TSHRMAPT | |
| SCHEMBL29398659 | 0.64 | ADORA2B (0.38) | ADORA2BHTTL3MBTL1TSHRMAPT | |
| SCHEMBL7793927 | 0.61 | CYP1A2 (0.73) | LMNAL3MBTL1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL10837423 | 0.61 | CYP3A4 (0.44) | ADORA2BHTTLMNASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL30122730 | 0.60 | CYP1A2 (0.71) | LMNAL3MBTL1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL9385726 | 0.60 | CYP3A4 (0.43) | ADORA2BHTTLMNAMAPK1SMN1; SMN2 | |
| SCHEMBL10838711 | 0.60 | CYP3A4 (0.43) | ADORA2BHTTLMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796251-B1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEM FAB (DE) | 2001-10-17 | — | — | EP | disclosed |
| US-6046329-A | Uracil derivatives | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-04-04 | — | — | US | disclosed |
| EP-0796251-A1 | URACIL DERIVATIVES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1996017831-A1 | URACIL DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-06-13 | — | — | WO | disclosed |