Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886390 | 0.82 | ALDH1A1 (0.68) | ALDH1A1NR4A1NR4A2NR4A3RAD52 | |
| SCHEMBL5886430 | 0.79 | ALDH1A1 (0.58) | ALDH1A1PIM1NR4A1NR4A2NR4A3 | |
| SCHEMBL5886293 | 0.78 | ALDH1A1 (0.70) | ALDH1A1NR4A1NR4A2NR4A3RAD52 | |
| SCHEMBL7801620 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KDM4EMEN1KMT2AKDM6B | |
| SCHEMBL31522172 | 0.77 | NR4A1 (0.60) | ALDH1A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL2223329 | 0.77 | NR4A1 (0.60) | ALDH1A1CSNK2A2CSNK2BPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL29816682 | 0.76 | NR4A1 (0.58) | ALDH1A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL30771576 | 0.76 | NR4A1 (0.58) | ALDH1A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL5886363 | 0.75 | ALDH1A1 (0.56) | ALDH1A1PIM1KDM4EMEN1KMT2A | |
| SCHEMBL5886496 | 0.75 | ALDH1A1 (0.52) | ALDH1A1CSNK2A2CSNK2BPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010034346-A1 | Pharmaceutical compounds | XENOVA LIMITED, BRITISH BODY CORPORATE (GB) | 2001-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034346-A1 | Pharmaceutical compounds | TOP1, ABCC1, TOP2A | ALDH1A1 461/4885CSNK2A2 421/4885CSNK2B 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.