Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12883329 | 0.87 | HDAC6 (0.47) | HDAC6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7796078 | 0.79 | HDAC6 (0.59) | HDAC6 | |
| SCHEMBL7793652 | 0.79 | HDAC6 (0.59) | HDAC6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1174178 | 0.69 | HDAC6 (0.62) | HDAC6HDAC1 | |
| SCHEMBL12883241 | 0.68 | HDAC6 (0.53) | HDAC6KDM4EKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7797509 | 0.66 | HDAC6 (0.46) | HDAC6HDAC1 | |
| SCHEMBL1174045 | 0.66 | HDAC6 (0.78) | HDAC6KDM4EALDH1A1HPGDPKM | |
| SCHEMBL7796577 | 0.63 | HDAC1 (0.49) | HDAC6KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL1174506 | 0.62 | HDAC6 (0.61) | HDAC6 | |
| SCHEMBL1174227 | 0.62 | HDAC6 (0.65) | HDAC6ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |