Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.46 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12883241 | 0.75 | HDAC6 (0.53) | HDAC6KDM1AHDAC3HDAC1HDAC8 | |
| SCHEMBL1174045 | 0.70 | HDAC6 (0.78) | HDAC6KDM1AHDAC1HDAC8 | |
| SCHEMBL1174178 | 0.69 | HDAC6 (0.62) | HDAC6HRH4HDAC3HDAC4HDAC1 | |
| SCHEMBL12883329 | 0.68 | HDAC6 (0.47) | HDAC6HDAC10HDAC8 | |
| SCHEMBL1174506 | 0.67 | HDAC6 (0.61) | HDAC6KDM1A | |
| SCHEMBL13562274 | 0.67 | HRH4 (0.62) | HRH4 | |
| SCHEMBL7799817 | 0.66 | HDAC6 (0.43) | HDAC6HDAC1 | |
| SCHEMBL1173979 | 0.66 | HDAC6 (0.66) | HDAC6KDM1AHDAC3HDAC1HDAC8 | |
| SCHEMBL1173867 | 0.66 | HDAC6 (0.66) | HDAC6KDM1AHDAC3HDAC1HDAC8 | |
| SCHEMBL11609333 | 0.66 | HRH4 (0.56) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |