SCHEMBL7800282

SCHEMBL7800282

CCCCOc1c(CCC)c(=O)oc2ccc(C)cc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.49
ALDH1A1 P00352 6/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 3/20 0.47
RAB9A P51151 3/20 0.47
HSD17B10 Q99714 3/20 0.47
NPC1 O15118 2/20 0.47
HSD17B3 P37058 1/20 0.46
ALDH1A2 O94788 2/20 0.45
ALDH2 P05091 2/20 0.45
ALDH1B1 P30837 2/20 0.45
ALDH1A3 P47895 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
TSHR P16473 2/20 0.42
SRC P12931 1/20 0.41
STS P08842 1/20 0.41
ABCB1 P08183 1/20 0.41
ABCC1 P33527 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7811491 0.82 CA12 (0.51) ALDH1A1KDM4EHPGDRAB9AHSD17B10
SCHEMBL19908186 0.81 MAPT (0.46) NQO1ALDH1A1KDM4EHPGDRAB9A
SCHEMBL7811513 0.77 NQO1 (0.76) NQO1ALDH1A1KDM4EHSD17B3ALDH1A2
SCHEMBL7806794 0.74 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDRAB9AHSD17B10
SCHEMBL19908187 0.74 MAPT (0.44) NQO1ALDH1A1KDM4EHPGDRAB9A
SCHEMBL19908166 0.74 MAPT (0.50) NQO1ALDH1A1KDM4EHPGDRAB9A
SCHEMBL8714423 0.72 NQO1 (0.46) NQO1ALDH1A1KDM4EHPGDRAB9A
SCHEMBL7811453 0.72 HSD17B3 (0.46) ALDH1A1KDM4EHPGDRAB9AHSD17B10
SCHEMBL12369514 0.71 NQO1 (0.62) NQO1ALDH1A1KDM4EHPGDRAB9A
SCHEMBL7811499 0.70 CA12 (0.48) ALDH1A1KDM4EHSD17B3MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0861242-B1 HETEROCYCLIC FUNGICIDES AVENTIS CROPSCIENCE UK LTD (GB) 2001-05-30 EP disclosed
US-6034121-A AGRICULTURE AGREVO UK LIMITED (GB) 2000-03-07 US disclosed
EP-0861242-A1 HETEROCYCLIC FUNGICIDES AgrEvo UK Limited (GB) 1998-09-02 EP disclosed
WO-1997013762-A1 HETEROCYCLIC FUNGICIDES AGREVO UK LIMITED (GB) 1997-04-17 WO disclosed