Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807635 | 0.88 | HDAC2 (0.36) | KCNH2NPC1RAB9AATMHDAC2 | |
| SCHEMBL7807514 | 0.81 | NPC1 (0.41) | KCNH2NPC1RAB9AATMHDAC2 | |
| SCHEMBL7800630 | 0.77 | MAPT (0.33) | KCNH2NPC1RAB9AATMKDM4E | |
| SCHEMBL7460300 | 0.77 | KCNH2 (0.38) | KCNH2ALDH1A1MAPTHSD17B10TDO2 | |
| SCHEMBL7807634 | 0.75 | KCNH2 (0.35) | KCNH2HDAC2HDAC1HDAC3 | |
| SCHEMBL7805954 | 0.74 | KCNH2 (0.37) | KCNH2HDAC2HDAC1HDAC3 | |
| SCHEMBL7808476 | 0.74 | CFTR (0.36) | HDAC2CETPKDM4EALDH1A1GAA | |
| SCHEMBL7807501 | 0.74 | CDK2 (0.30) | — | |
| SCHEMBL7805999 | 0.74 | TDP1 (0.43) | KCNH2NPC1RAB9AATMHDAC2 | |
| SCHEMBL7808585 | 0.73 | KCNH2 (0.46) | KCNH2NPC1RAB9AATMHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |