Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 14/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800617 | 0.88 | KCNH2 (0.37) | HDAC2HDAC1HDAC3KCNH2NPC1 | |
| SCHEMBL7805999 | 0.82 | TDP1 (0.43) | HDAC2HDAC1HDAC3KCNH2NPC1 | |
| SCHEMBL7807616 | 0.78 | AR (0.32) | HDAC2HDAC1HDAC3KCNH2NPC1 | |
| SCHEMBL7461291 | 0.78 | KCNH2 (0.36) | KCNH2TDO2ALDH1A1MAPT | |
| SCHEMBL7808585 | 0.77 | KCNH2 (0.46) | HDAC2HDAC1HDAC3KCNH2NPC1 | |
| SCHEMBL7807625 | 0.77 | CETP (0.33) | CETP | |
| SCHEMBL7812289 | 0.76 | — | — | |
| SCHEMBL7808836 | 0.76 | CFTR (0.37) | ALDH1A1GAAMAPTCETP | |
| SCHEMBL7808600 | 0.75 | HDAC2 (0.39) | HDAC2HDAC1HDAC3KCNH2NPC1 | |
| SCHEMBL7807514 | 0.74 | NPC1 (0.41) | HDAC2HDAC1HDAC3KCNH2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |