Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778065 | 0.96 | — | — | |
| SCHEMBL184079 | 0.80 | — | — | |
| SCHEMBL5713286 | 0.80 | ALDH1A1 (0.39) | ALDH1A1 | |
| Ethylene SCHEMBL10456431 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| Bicarbonate SCHEMBL27847276 | 0.78 | ALDH1A1 (0.41) | ALDH1A1 | |
| Urea SCHEMBL27684261 | 0.77 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL11310102 | 0.76 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL3630010 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL1412263 | 0.75 | HPGD (0.41) | ALDH1A1 | |
| SCHEMBL5172542 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951496-B1 | ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS | GEORGIA PACIFIC RESINS (US) | 2001-12-19 | — | — | EP | disclosed |
| EP-0951496-A2 | ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS | GEORGIA-PACIFIC RESINS, INC. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998030596-A2 | ALKYD AND ARALKYD DERIVATIVES OF PHENOLIC POLYMERS | GEORGIA-PACIFIC RESINS, INC. (US) | 1998-07-16 | — | — | WO | disclosed |
| US-5770750-A | Alkyd and aralkyd derivatives of phenolic polymers | GEORGIA-PACIFIC RESINS, INC. (US) | 1998-06-23 | — | — | US | disclosed |