Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20070629 | 0.82 | GBA1 (0.52) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL6774385 | 0.75 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR1AMKNK1 | |
| Hydrochloric Acid SCHEMBL9041147 | 0.74 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR1AMKNK1 | |
| SCHEMBL8646489 | 0.71 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3HTR1AKCNH2 | |
| SCHEMBL895063 | 0.71 | GBA1 (0.66) | SLC6A2SLC6A4SLC6A3HTR1A | |
| Bromide SCHEMBL7246786 | 0.69 | GBA1 (0.63) | SLC6A2SLC6A4SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL4247331 | 0.69 | GBA1 (0.63) | SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL20002871 | 0.69 | HTR6 (0.36) | SLC6A2SLC6A4SLC6A3HTR1ATACR1 | |
| SCHEMBL777796 | 0.68 | IDO1 (0.46) | — | |
| Trifluoroacetic Acid SCHEMBL4771690 | 0.68 | PRCP (0.39) | SLC6A2SLC6A4SLC6A3HTR1ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010039286-A1 | 2-aryl indole derivatives and their use as therapeutic agents | DINNELL KEVIN (GB) | 2001-11-08 | — | — | US | disclosed |
| US-5854268-A | Azetidine, pyrrolidine and piperidine derivatives | MERCK SHARP & DOHME, LTD. (GB) | 1998-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039286-A1 | 2-aryl indole derivatives and their use as therapeutic agents | IDO1, IDO2, CNR2 | SLC6A2 1001/4885SLC6A4 157/4885SLC6A3 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.