Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807487 | 0.92 | POLB (0.44) | PDE4BPDE7APDE2APDE5APDE1B | |
| SCHEMBL7805962 | 0.83 | PDE4B (0.40) | PDE4BPDE7APDE2APDE5APDE1B | |
| SCHEMBL7807574 | 0.80 | TAAR1 (0.40) | ADORA2AADORA1ADORA2BPOLBHSD17B10 | |
| SCHEMBL7800808 | 0.78 | ADORA2A (0.41) | PDE4BPDE7APDE2APDE5APDE1B | |
| SCHEMBL7461915 | 0.78 | PTGER4 (0.43) | PDE3APTGER4HTTSMN1; SMN2HSD17B10 | |
| SCHEMBL7805952 | 0.75 | TAAR1 (0.46) | ADORA2AADORA1ADORA2BPOLBHSD17B10 | |
| SCHEMBL7809829 | 0.75 | PTGER4 (0.40) | PDE3APTGER4POLBHTTSMN1; SMN2 | |
| SCHEMBL7806017 | 0.75 | GAA (0.41) | PTGER4POLBHTTSMN1; SMN2HSD17B10 | |
| SCHEMBL7800685 | 0.74 | TAAR1 (0.35) | ADORA2AADORA1POLBHSD17B10TAAR1 | |
| SCHEMBL7808816 | 0.74 | PTGER4 (0.40) | PTGER4HTTSMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |