SCHEMBL7807487

SCHEMBL7807487

COCCNc1ccc(N)cc1-c1ccco1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
PDE4B Q07343 5/20 0.41
PTGER4 P35408 2/20 0.41
NCF1 P14598 2/20 0.40
ADORA2A P29274 4/20 0.39
ADORA1 P30542 4/20 0.39
ADORA3 P0DMS8 2/20 0.39
TRIM33 Q9UPN9 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
APAF1 O14727 1/20 0.37
THRB P10828 1/20 0.37
PABPC1 P11940 1/20 0.37
PTPN7 P35236 1/20 0.37
RECQL P46063 1/20 0.37
DUSP3 P51452 1/20 0.37
BLM P54132 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7800935 0.92 PDE4B (0.43) POLBPDE4BPTGER4NCF1ADORA2A
SCHEMBL7807574 0.82 TAAR1 (0.40) POLBADORA2AADORA1ADORA3TAAR1
SCHEMBL7805962 0.80 PDE4B (0.40) POLBPDE4BADORA2AADORA1ADORA3
SCHEMBL6570689 0.78 PTGER4 (0.48) PTGER4NCF1ALDH1A1MAPTKDM4E
SCHEMBL6572960 0.78 PTGER4 (0.51) PTGER4NCF1ALDH1A1MAPTKDM4E
SCHEMBL6574666 0.77 PTGER4 (0.50) POLBPTGER4NCF1ALDH1A1MAPT
SCHEMBL6572005 0.77 PTGER4 (0.50) POLBPTGER4NCF1ALDH1A1MAPT
SCHEMBL6572456 0.77 PTGER4 (0.50) POLBPTGER4NCF1ALDH1A1MAPT
SCHEMBL7805952 0.77 TAAR1 (0.46) POLBADORA2AADORA1ADORA3TAAR1
Hydrochloric Acid SCHEMBL6572054 0.77 PTGER4 (0.50) PTGER4NCF1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed