Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 7/20 | 0.61 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8149118 | 0.99 | SLC9A1 (0.60) | SLC9A1SLC9A2CYP3A4 | |
| SCHEMBL9018715 | 0.89 | SLC9A1 (0.59) | SLC9A1SLC9A2 | |
| Hydrochloric Acid SCHEMBL8812986 | 0.87 | SLC9A1 (0.63) | SLC9A1SLC9A2 | |
| SCHEMBL8610270 | 0.86 | SLC9A1 (0.55) | SLC9A1SLC9A2 | |
| SCHEMBL29586404 | 0.84 | AR (0.41) | SLC9A1SLC9A2 | |
| SCHEMBL7832481 | 0.81 | SLC9A1 (0.66) | SLC9A1SLC9A2 | |
| SCHEMBL9018675 | 0.80 | SLC9A1 (0.57) | SLC9A1SLC9A2 | |
| SCHEMBL9194596 | 0.80 | SLC9A1 (0.68) | SLC9A1SLC9A2 | |
| SCHEMBL8816511 | 0.80 | SLC9A1 (0.68) | SLC9A1SLC9A2 | |
| SCHEMBL6935465 | 0.80 | SLC9A1 (0.72) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | claimed |
| EP-0743301-B1 | Benzoylguanidines containing fluorine | MERCK PATENT GMBH (DE) | 2001-08-29 | — | — | EP | disclosed |
| US-5747539-A | Fluorine-containing benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-05 | — | — | US | disclosed |
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |