SCHEMBL7801043

SCHEMBL7801043

CCc1ccc(CCl)cc1.[Zn]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
CYP2A6 P11509 1/20 0.44
LPL P06858 1/20 0.44
LIPG Q9Y5X9 1/20 0.44
MGLL Q99685 1/20 0.43
POLB P06746 2/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PLAU P00749 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52437 0.97 TP53 (0.50) TP53TSHRMAPK1ATMTDP1
Benzene SCHEMBL28650497 0.92 TP53 (0.60) TP53TSHRMAPK1ATMTDP1
SCHEMBL3599879 0.89 NPC1 (0.48) TP53TSHRMAPK1ATMTDP1
SCHEMBL9505702 0.83 SMN1; SMN2 (0.49) TP53TSHRMAPK1ATMTDP1
SCHEMBL97582 0.80 CA1 (0.52) TSHRTDP1TAAR1MGLLALDH1A1
SCHEMBL36295 0.80 TP53 (0.67) TP53TSHRMAPK1ATMTDP1
SCHEMBL10731985 0.79 ALDH1A1 (0.57) TDP1POLBNPC1GAAALDH1A1
SCHEMBL15201702 0.78 TP53 (0.50) TP53TSHRMAPK1ATMTDP1
SCHEMBL31498555 0.77 TP53 (0.62) TP53TSHRMAPK1ATMTDP1
Hydrogen Sulfide SCHEMBL29290777 0.77 TP53 (0.62) TP53TSHRMAPK1ATMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001226312-A METHOD FOR PRODUCING 3-PHENYLPROPYL KETONE COMPOUND UBE IND LTD 2001-08-21 JP disclosed