Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801150 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL7801102 | 0.74 | MAPT (0.39) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7803784 | 0.73 | MAPT (0.38) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL7805224 | 0.72 | MAPT (0.39) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL7795295 | 0.68 | MAPT (0.40) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL4269080 | 0.65 | MAPT (0.49) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL8463831 | 0.64 | ALDH1A1 (0.44) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4618823 | 0.63 | MAPT (0.47) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL9542886 | 0.63 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 | |
| SCHEMBL9542100 | 0.62 | ALDH1A1 (0.43) | ALDH1A1MAPTGAAMDM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956016-A4 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | UNIV FLORIDA STATE (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0956016-A1 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | Florida State University (US) | 1999-11-17 | — | — | EP | disclosed |
| WO-1998014190-A9 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | — | 1998-07-30 | — | — | WO | disclosed |
| WO-1998014190-A1 | PHARMACEUTICAL COMPOUNDS COMPRISING POLYAMINES SUBSTITUTED WITH ELECTRON-AFFINIC GROUPS | FLORIDA STATE UNIVERSITY (US) | 1998-04-09 | — | — | WO | disclosed |