SCHEMBL7801199

SCHEMBL7801199

NOC1CC2CCC1CC2

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9077300 0.86
SCHEMBL7801196 0.72 ATM (0.31) ATM
SCHEMBL26498564 0.72 ATM (0.31) ATM
SCHEMBL15291257 0.70
SCHEMBL28316693 0.68 LMNA (0.32)
SCHEMBL409200 0.67 ATM (0.32) ATM
SCHEMBL14268221 0.67 IRAK4 (0.34)
SCHEMBL30394028 0.67 ATM (0.32) ATM
SCHEMBL11079349 0.65 ATM (0.50) ATM
SCHEMBL2654180 0.65 ATM (0.46) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582829-B1 9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines as antibiotic agents AMERICAN CYANAMID CO (US) 2001-09-12 EP claimed
US-5495031-A Process for the production of 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1996-02-27 US claimed
US-5466684-A 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1995-11-14 US claimed
US-5420272-A 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1995-05-30 US claimed
US-5371076-A ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1994-12-06 US claimed
US-5328902-A Antibiotics AMERICAN CYANAMID CO. (US) 1994-07-12 US claimed
EP-0582829-B1 9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines as antibiotic agents AMERICAN CYANAMID CO (US) 2001-09-12 EP disclosed