Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237833 | 0.81 | NPC1 (0.41) | — | |
| SCHEMBL6018293 | 0.80 | ATM (0.50) | MMP9ATMCTNNB1L3MBTL1SLC1A3 | |
| SCHEMBL1902233 | 0.80 | ATM (0.50) | MMP9ATMCTNNB1L3MBTL1SLC1A3 | |
| Hydrochloric Acid SCHEMBL9632609 | 0.79 | ATM (0.49) | MMP9ATMCTNNB1L3MBTL1SLC1A3 | |
| Hydrochloric Acid SCHEMBL9630734 | 0.79 | ATM (0.49) | MMP9ATMCTNNB1L3MBTL1SLC1A3 | |
| Hydrochloric Acid SCHEMBL7066174 | 0.79 | ATM (0.49) | MMP9ATMCTNNB1L3MBTL1SLC1A3 | |
| SCHEMBL16450886 | 0.78 | CTNNB1 (0.54) | NLNMMP9CTNNB1L3MBTL1SLC1A3 | |
| SCHEMBL16261558 | 0.78 | CTNNB1 (0.54) | NLNMMP9CTNNB1L3MBTL1SLC1A3 | |
| SCHEMBL15686536 | 0.78 | CTNNB1 (0.54) | NLNMMP9CTNNB1L3MBTL1SLC1A3 | |
| SCHEMBL26768357 | 0.78 | KDM4E (0.64) | MMP9L3MBTL1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721449-B1 | INHIBITORS OF BETA-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMA INC (US) | 2001-12-19 | — | — | EP | disclosed |
| US-5977074-A | THERAPY FOR ALZHEIMER'S DISEASE | MERRELL PHARMACEUTICALS, INC. (US) | 1999-11-02 | — | — | US | disclosed |