Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | LTA4H | P09960 | 5/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine SCHEMBL7801537 | 1.00 | KMT2A (0.41) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Lysine SCHEMBL7802634 | 0.97 | KMT2A (0.40) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Lysine SCHEMBL7802639 | 0.97 | KMT2A (0.40) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Phenylacetic Acid SCHEMBL7798281 | 0.95 | LTA4H (0.42) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Phenylacetic Acid SCHEMBL7798109 | 0.95 | LTA4H (0.42) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Phenylacetic Acid SCHEMBL7798111 | 0.95 | LTA4H (0.42) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Ornithine SCHEMBL7792680 | 0.93 | MEN1 (0.46) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Lysine SCHEMBL7798100 | 0.92 | LTA4H (0.44) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Lysine SCHEMBL7798098 | 0.92 | LTA4H (0.44) | KMT2AMEN1LTA4HSLC1A3SLC1A2 | |
| Lysine SCHEMBL7800517 | 0.90 | MEN1 (0.45) | KMT2AMEN1LTA4HSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |