Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.73 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.73 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.73 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.73 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.73 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.73 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.73 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.73 |
| ▸ | ACHE | P22303 | 1/20 | 0.69 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CCR2 | P41597 | 2/20 | 0.63 |
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5378277 | 0.93 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1220329 | 0.88 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4139290 | 0.88 | HDAC3 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8363043 | 0.86 | BCHE (0.75) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9046417 | 0.85 | ACHE (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5371060 | 0.85 | HDAC3 (0.82) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28642184 | 0.84 | HDAC3 (0.77) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL23630638 | 0.84 | HDAC3 (0.80) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL11909092 | 0.82 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5823 | 0.82 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673927-B1 | piperidines as anticholinergic agents | EISAI CO LTD (JP) | 2001-09-19 | — | — | EP | claimed |
| EP-0673927-B1 | piperidines as anticholinergic agents | EISAI CO LTD (JP) | 2001-09-19 | — | — | EP | disclosed |