Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893128 | 0.98 | SPHK1 (0.47) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL751283 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL8517654 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27970625 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL3730643 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL8652229 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL4169780 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL17501649 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL29879550 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB | |
| SCHEMBL27612145 | 0.83 | SPHK1 (0.60) | SPHK1CYP2D6LMNAGMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177469-B1 | ANTIUTOR AGENTS; AUTOIMMUNE DISEASES | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2001-01-23 | — | — | US | claimed |
| EP-0854708-B1 | LIPID ALCOHOLS AS NEW IMMUNOSUPPRESSIVE AND ANTIVIRAL DRUGS | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6177469-B1 | ANTIUTOR AGENTS; AUTOIMMUNE DISEASES | HEIDELBERG PHARMA HOLDING GMBH (DE) | 2001-01-23 | — | — | US | disclosed |