SCHEMBL7801577

SCHEMBL7801577

CC(=O)OCCN(CCC#N)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TP53 P04637 1/20 0.42
MDM2 Q00987 1/20 0.42
MLYCD O95822 1/20 0.41
RAD52 P43351 1/20 0.41
POLB P06746 1/20 0.40
ALDH1A1 P00352 7/20 0.39
KDM4E B2RXH2 1/20 0.39
THRB P10828 1/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10769049 0.92 MEN1 (0.44) USP2HSD17B10MEN1KMT2ATP53
SCHEMBL3395917 0.88 RAD52 (0.49) MEN1KMT2ARAD52ALDH1A1TSHR
SCHEMBL11669714 0.87 RAD52 (0.42) USP2HSD17B10MEN1KMT2ARAD52
SCHEMBL10997339 0.85 ALDH1A1 (0.43) USP2HSD17B10MEN1KMT2ATP53
SCHEMBL7512736 0.84 TDP1 (0.49) USP2HSD17B10MEN1KMT2ATP53
SCHEMBL11341671 0.84 KMT2A (0.42) USP2HSD17B10MEN1KMT2AMLYCD
SCHEMBL11095947 0.83 HSD17B10 (0.43) USP2HSD17B10MEN1KMT2ATP53
SCHEMBL10769699 0.83 USP2 (0.43) USP2HSD17B10MEN1KMT2ATP53
SCHEMBL11521086 0.83 USP2 (0.46) USP2HSD17B10MEN1KMT2ATP53
SCHEMBL11408705 0.82 USP2 (0.58) USP2HSD17B10MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118109062-A One-step preparation method for synthesizing and sanding disperse orange 30 superfine liquid dye 大连理工大学 2024-05-31 CN claimed
CN-117732417-A Continuous production system and process of N-cyanoethyl-N-acetoxyethyl aniline 浙江迪邦化工有限公司 2024-03-22 CN claimed
CN-115044226-A 3-amino-5-nitrobenzoisothiazole-based dye and preparation method thereof 金塔县晋泰森新材料科技有限公司 2022-09-13 CN claimed
CN-114437560-A Preparation process of disperse dye 苏州市罗森助剂有限公司 2022-05-06 CN claimed
CN-113968796-A Preparation method of azo dye with excellent environment-friendly application performance 安徽清科瑞洁新材料有限公司 2022-01-25 CN claimed
US-5162511-A Nitrosating and diazotizing reagents and reactions GAMBLIN RODGER L (US) 1992-11-10 US claimed
CN-113968796-B Preparation method of brown azo-like dye 安徽清科瑞洁新材料有限公司 2024-09-24 CN disclosed
CN-118530605-A Azo disperse dye and preparation method and application thereof 蓬莱嘉信染料化工股份有限公司 2024-08-23 CN disclosed
CN-115044225-B Fluorine-containing alkali-resistant disperse dye with high wet processing fastness and preparation method thereof 南通大学 2024-07-30 CN disclosed
CN-118109062-A One-step preparation method for synthesizing and sanding disperse orange 30 superfine liquid dye 大连理工大学 2024-05-31 CN disclosed
CN-118109062-A One-step preparation method for synthesizing and sanding disperse orange 30 superfine liquid dye 大连理工大学 2024-05-31 CN disclosed
CN-117756672-A Refining method of N-cyanoethylaniline 浙江迪邦化工有限公司 2024-03-26 CN disclosed
CN-117732417-A Continuous production system and process of N-cyanoethyl-N-acetoxyethyl aniline 浙江迪邦化工有限公司 2024-03-22 CN disclosed
US-4105655-A PHENYL-AZO-ANILINO DYESTUFF BAYER AKTIENGESELLSCHAFT (DE) 1978-08-08 US disclosed
US-4028323-A WITH A SUBSTITUTED AMINOBENZENE CIBA-GEIGY AG (CH) 1977-06-07 US disclosed
US-4013632-A SYNTHETIC FIBERS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-22 US disclosed
US-3978040-A Process for the preparation of cyanoazo compounds by reacting halogenoazo compounds with CuCN in an aqueous media in the presence of a nitrogen base BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3962209-A PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 US disclosed
US-3932379-A Water-soluble maroon and rubine sulphodiphenylazophenyl- or naphthylazoaniline dyes for polyamide fibers Althouse Tertre en abrege "Atsa" societe anonyme (BE) 1976-01-13 US disclosed