Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801639 | 1.00 | BRD4 (0.38) | BRD4BRD2PIK3CDL3MBTL1CHRM2 | |
| SCHEMBL31072384 | 0.98 | L3MBTL1 (0.37) | BRD4BRD2PIK3CDL3MBTL1CHRM2 | |
| SCHEMBL195054 | 0.93 | — | — | |
| SCHEMBL19448367 | 0.93 | — | — | |
| SCHEMBL11827149 | 0.93 | — | — | |
| SCHEMBL8894744 | 0.84 | — | — | |
| SCHEMBL8895639 | 0.84 | — | — | |
| SCHEMBL10887603 | 0.82 | BRD4 (0.41) | BRD4BRD2PIK3CDL3MBTL1CHRM2 | |
| SCHEMBL1435579 | 0.82 | — | — | |
| SCHEMBL7793984 | 0.78 | PIK3CD (0.36) | BRD4BRD2PIK3CDL3MBTL1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371238-A | Reacting 1-/n-alkenyl/-azacycloalkan-2-one with alkyl mercaptan using free radical initiator, reducing, distilling to purify | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1994-12-06 | — | — | US | claimed |
| EP-0555483-B1 | PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE | HISAMITSU PHARMACEUTICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5371238-A | Reacting 1-/n-alkenyl/-azacycloalkan-2-one with alkyl mercaptan using free radical initiator, reducing, distilling to purify | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0555483-A1 | PROCESS FOR PRODUCING AZACYCLOALKANE DERIVATIVE | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1993-08-18 | — | — | EP | disclosed |