Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.70 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806929 | 0.93 | CYSLTR1 (0.74) | CYSLTR1ALOX5PDE4APDE4BPDE4C | |
| SCHEMBL7806933 | 0.91 | CYSLTR1 (0.77) | CYSLTR1ALOX5PDE4APDE4BPDE4C | |
| SCHEMBL7801790 | 0.85 | CYSLTR1 (0.81) | CYSLTR1ALOX5PDE4APDE4BPDE4C | |
| SCHEMBL7809882 | 0.82 | CYSLTR1 (0.76) | CYSLTR1ALOX5PDE4APDE4BPDE4C | |
| SCHEMBL7801904 | 0.82 | CYSLTR1 (0.67) | CYSLTR1ALOX5PDE4APDE4BPDE4C | |
| SCHEMBL9504243 | 0.81 | CYSLTR1 (0.68) | CYSLTR1ALOX5PDE4APDE4BPDE4C | |
| SCHEMBL7004947 | 0.81 | CYSLTR1 (0.85) | CYSLTR1ALOX5GPBAR1 | |
| SCHEMBL9063339 | 0.80 | CYSLTR1 (0.56) | CYSLTR1 | |
| SCHEMBL9827537 | 0.80 | CYSLTR1 (0.83) | CYSLTR1ALOX5GPBAR1 | |
| SCHEMBL9589932 | 0.80 | ALOX5 (0.66) | CYSLTR1ALOX5PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775133-B1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2001-05-30 | — | — | EP | disclosed |
| WO-1996004267-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |