Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806673 | 0.90 | LTB4R (0.47) | LTB4RPDE10ACYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7801438 | 0.90 | LTB4R (0.47) | LTB4RPDE10ACYSLTR1CYSLTR2 | |
| SCHEMBL7806716 | 0.89 | LTB4R (0.47) | LTB4RPDE10ACYSLTR1GPBAR1ALOX5AP | |
| SCHEMBL7813330 | 0.89 | LTB4R (0.47) | LTB4RPDE10ACYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7808147 | 0.89 | LTB4R (0.47) | LTB4RPDE10ACYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL7801813 | 0.87 | LTB4R (0.47) | LTB4RPDE10ACYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7810770 | 0.87 | LTB4R (0.46) | LTB4RPDE10ACYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7813383 | 0.85 | LTB4R (0.43) | LTB4RPDE10ACYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL7801372 | 0.85 | LTB4R (0.43) | LTB4RPDE10ACYSLTR1CYSLTR2ALOX5AP | |
| SCHEMBL13765165 | 0.84 | PDE10A (0.55) | LTB4RPDE10ACYSLTR1GPBAR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |