Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801742 | 1.00 | KDM4E (0.47) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 | |
| SCHEMBL7801788 | 0.89 | POLB (0.51) | KDM4EABCG2KMT2AMAPTHTT | |
| SCHEMBL7803835 | 0.89 | POLB (0.51) | KDM4EABCG2KMT2AMAPTHTT | |
| SCHEMBL7802593 | 0.85 | HSD17B10 (0.50) | KDM4ECYP1A2CYP2C19CYP2C9ABCG2 | |
| SCHEMBL7802590 | 0.85 | HSD17B10 (0.50) | KDM4ECYP1A2CYP2C19CYP2C9ABCG2 | |
| SCHEMBL7805468 | 0.84 | ABL1 (0.46) | KDM4EKMT2AMAPTNR4A2GLA | |
| SCHEMBL7795848 | 0.84 | SMN1; SMN2 (0.42) | KDM4ECYP1A2CYP2C19CYP2D6KMT2A | |
| SCHEMBL7805464 | 0.84 | ABL1 (0.46) | KDM4EKMT2AMAPTNR4A2GLA | |
| SCHEMBL7795845 | 0.84 | SMN1; SMN2 (0.42) | KDM4ECYP1A2CYP2C19CYP2D6KMT2A | |
| Methyl 2,5-Dimethoxybenzoate SCHEMBL2091289 | 0.77 | MAPT (0.66) | KDM4ECYP1A2CYP2C19CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |