Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801764 | 1.00 | TSHR (0.46) | TSHRHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL7694772 | 0.90 | TSHR (0.47) | TSHRHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL7694769 | 0.87 | TSHR (0.44) | TSHRHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL7694770 | 0.87 | TSHR (0.44) | TSHRHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL7802444 | 0.84 | KDM4E (0.43) | KDM4ECYP1A2CYP2C9ALDH1A1MEN1 | |
| SCHEMBL7802445 | 0.84 | KDM4E (0.43) | KDM4ECYP1A2CYP2C9ALDH1A1MEN1 | |
| SCHEMBL13342826 | 0.78 | TSHR (0.57) | TSHRHTR2AHTR2CHTR2BKDM4E | |
| SCHEMBL7804525 | 0.78 | LMNA (0.38) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7804527 | 0.78 | LMNA (0.38) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8024241 | 0.75 | NOTUM (0.41) | KDM4EALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |