Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801842 | 0.92 | MAOB (0.45) | RAB9ANPC1SMN1; SMN2TP53MAOB | |
| SCHEMBL7808651 | 0.91 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2TP53MAOB | |
| SCHEMBL7808665 | 0.86 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7808623 | 0.84 | RAB9A (0.43) | RAB9ANPC1SMN1; SMN2TP53MAOB | |
| SCHEMBL7801871 | 0.83 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7808657 | 0.82 | MAOB (0.45) | RAB9ANPC1SMN1; SMN2TP53MAOB | |
| Hydrochloric Acid SCHEMBL8480228 | 0.82 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7807186 | 0.81 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2TP53MAOB | |
| SCHEMBL7810775 | 0.81 | SMN1; SMN2 (0.57) | RAB9ANPC1SMN1; SMN2TP53TSHR | |
| SCHEMBL7808402 | 0.81 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820990-B1 | Benzimidazole, benzoxazole, and benzothiazole derivatives useful as interleukin 1beta inhibitors | ADIR (FR) | 2001-01-17 | — | — | EP | disclosed |
| US-5972968-A | INTERLEUKIN INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-10-26 | — | — | US | disclosed |
| EP-0820990-A2 | Novel benzimidazole, benzoxazole, and benzothiazole derivatives useful as interleukin 1beta inhibitors | ADIR ET COMPAGNIE (FR) | 1998-01-28 | — | — | EP | disclosed |