SCHEMBL7801971

SCHEMBL7801971

O=C(NCCCc1ccc(-c2nnn[nH]2)cc1)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 8/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7808360 0.95 CYSLTR1 (0.76) CYSLTR1
SCHEMBL7808452 0.91 CYSLTR1 (0.64) CYSLTR1
SCHEMBL8734229 0.85 CYSLTR1 (0.60) CYSLTR1
SCHEMBL7808321 0.83 CYSLTR1 (0.56) CYSLTR1
SCHEMBL7810015 0.82 CYSLTR1 (0.54) CYSLTR1
SCHEMBL9828218 0.81 CYSLTR1 (0.61) CYSLTR1
SCHEMBL9830499 0.81 CYSLTR1 (0.64) CYSLTR1
SCHEMBL7801976 0.81 CYSLTR1 (0.52) CYSLTR1
SCHEMBL7810751 0.80 CYSLTR1 (0.74) CYSLTR1
SCHEMBL8735672 0.80 CYSLTR1 (0.65) CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775133-B1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION MENARINI LAB (ES) 2001-05-30 EP claimed
WO-1996004267-A1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION LABORATORIOS MENARINI S.A. (ES) 1996-02-15 WO claimed
EP-0775133-B1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION MENARINI LAB (ES) 2001-05-30 EP disclosed
EP-0775133-A1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION LABORATORIOS MENARINI S.A. (ES) 1997-05-28 EP disclosed
WO-1996004267-A1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION LABORATORIOS MENARINI S.A. (ES) 1996-02-15 WO disclosed