Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828218 | 0.90 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2 | |
| SCHEMBL9830499 | 0.90 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2 | |
| SCHEMBL8735672 | 0.90 | CYSLTR1 (0.65) | CYSLTR1CYSLTR2 | |
| SCHEMBL9828138 | 0.88 | CYSLTR1 (0.63) | CYSLTR1CYSLTR2 | |
| SCHEMBL9829185 | 0.88 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10420344 | 0.88 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9829921 | 0.85 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7801971 | 0.85 | CYSLTR1 (0.69) | CYSLTR1 | |
| SCHEMBL7101389 | 0.85 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 | |
| SCHEMBL7715802 | 0.85 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874826-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1998-11-04 | — | — | EP | claimed |
| WO-1997024331-A1 | NAPHTHALENE QUINOLINES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-07-10 | — | — | WO | claimed |