Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811290 | 0.90 | KDM4E (0.47) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7622499 | 0.86 | CYP1A1 (0.57) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7622494 | 0.86 | CYP1A1 (0.57) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7620386 | 0.83 | NPC1 (0.50) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7620399 | 0.83 | NPC1 (0.50) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7621487 | 0.81 | KDM4E (0.49) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7621478 | 0.81 | KDM4E (0.49) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7621431 | 0.78 | KDM4E (0.51) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL7621435 | 0.78 | KDM4E (0.51) | KMT2AMEN1NPC1RAB9AKDM4E | |
| SCHEMBL1589647 | 0.77 | PSEN1 (0.65) | KMT2AMEN1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830345-B1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 2001-09-05 | — | — | EP | claimed |